Bartonella in the news

Two articles about Bartonella, first the link the a conference then further down an abstract about the persistance of Bartonella.

7th International Conference on Bartonella as Animal and Human Pathogens

April 25 – 28, 2012

Raleigh, North Carolina, USA

On behalf of the Scientific and Organizing Committees for the 7th International Conference on Bartonella as Animal and Human Pathogens, it is our pleasure to welcome you to Raleigh, North Carolina. Assuming Mother Nature cooperates, this is an absolutely beautiful time of the year in our part of the world.

Our conference is close at hand but there is still time!

Full Conference Registration is $395. Registration includes all lectures and poster sessions; printed proceedings, Wednesday evening reception; breakfasts, breaks and lunches (Thursday – Saturday); Thursday evening dinner at the Museum of Natural Sciences, Duke Lemur Center tour Saturday (registration required for tour).

Single Day Registration is $125. Includes breakfast, lunch and refreshments at the breaks but does NOT include the gala dinner or Lemur Center tour. Single day registration is available for any one day of the conference.

Persistence of Bartonella spp. stealth pathogens: from subclinical infections to vasoproliferative tumor formation

Abstract

Bartonella spp. are facultative intracellular bacteria that typically cause a long-lasting intraerythrocytic bacteremia in their mammalian reservoir hosts, thereby favoring transmission by blood-sucking arthropods. In most cases, natural reservoir host infections are subclinical and the relapsing intraerythrocytic bacteremia may last weeks, months, or even years. In this review, we will follow the infection cycle of Bartonella spp. in a reservoir host, which typically starts with an intradermal inoculation of bacteria that are superficially scratched into the skin from arthropod feces and terminates with the pathogen exit by the blood-sucking arthropod. The current knowledge of bacterial countermeasures against mammalian immune response will be presented for each critical step of the pathogenesis. The prevailing models of the still-enigmatic primary niche and the anatomical location where bacteria reside, persist, and are periodically seeded into the bloodstream to cause the typical relapsing Bartonella spp. bacteremia will also be critically discussed. The review will end up with a discussion of the ability of Bartonella spp., namely Bartonella henselae,Bartonella quintana, and Bartonella bacilliformis, to induce tumor-like vascular deformations in humans having compromised immune response such as in patients with AIDS.

 





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