Erythromycin resistance in Borrelia burgdorferi.

 Antimicrob Agents Chemother. 2002 Nov;46,11:3637-40. Erythromycin resistance in 
Borrelia burgdorferi. Terekhova D, Sartakova ML, Wormser GP, Schwartz I, Cabello FC.
Departments of Microbiology and Immunology, New York Medical College, Valhalla, New York 
10595, USA.
Susceptibility testing of laboratory strains and clinical isolates of Borrelia burgdorferi
indicates that resistance to erythromycin is present in them. Evaluation of the MICs, minimal 
bactericidal concentrations, and kinetics of bacterial killing of erythromycin suggests that this 
resistance is increased by preexposure to the antibiotic, is dependent on inoculum size, and may 
be the result of selection of subpopulations of bacterial cells with increased resistance




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