MILFORD, Conn.–(BUSINESS WIRE)–Patients with clinical Lyme disease may not be infected by the Lyme disease spirochete (bacteria), but in fact by other related bacteria, such as Borrelia miyamotoi and a new, as yet unnamed spirochete according to a paper just published this month in the International Journal of Molecular Sciences http://www.mdpi.com/1422-0067/15/3/4284/.
“The diagnoses of Lyme disease based on clinical manifestations, serological findings and detection of infectious agents often contradict each other…”
“The gateway to new DNA sequencing tests is proper polymerase chain reaction (PCR), and we have designed a pair of genus-specific PCR primers to detect all pathogenic spirochetes, including Borrelia burgdorferi, Borrelia miyamotoiand other related borreliae in this group and to prepare the templates for direct DNA sequencing,” said Sin Hang Lee, MD, a Milford Hospital pathologist and lead author of the paper. DNA sequencing is the accepted gold standard for all nucleic acid-based diagnostic tests.
Lyme Disease DNA Testing
The Molecular Diagnostics Department of Milford Medical Laboratory is a licensed clinical laboratory in the US and is offering a combined DNA Sequencing-based diagnostic test for Borrelia burgdorferi and Borrelia miyamotoi, the infectious agent of a similar Lyme disease-like illness found recently in the United States.
All tested samples are issued an official laboratory report as well as an accompanying DNA sequencing electropherogram and GenBank BLAST alignment analysis if the result is positive.