Rapidly progressive frontal-type dementia associated with Lyme disease.

 J Neuropsychiatry Clin Neurosci. 1995 Summer;7,3:345-7. Rapidly progressive frontal-type 
dementia associated with Lyme disease. Waniek C, Prohovnik I, Kaufman MA, Dwork AJ.
40New York State Psychiatric Institute, NY 10032, USA.
The authors report a case of fatal neuropsychiatric Lyme disease, LD, that was expressed 
clinically by progressive frontal lobe dementia and pathologically by severe subcortical
degeneration. Antibiotic treatment resulted in transient improvement, but the patient 
relapsed after the antibiotics were discontinued. LD must be considered even in cases with 
purely psychiatric presentation, and prolonged antibiotic therapy may be necessary




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