Febrile Seizures in children in WI caused by Tick Borne Infections?

Lyme disease, human granulocytic ehrlichiosis (HGE), and babesiosis are tickborne infections that are indigenous to Wisconsin. To assess their importance as a cause of nonspecific fever, we recruited patients with
febrile illness at 10 clinics in northwestern Wisconsin from May through August of both 1997 and 1998.
Eligible patients had a temperature 138.0C but no rash or other localizing source. Acute and convalescent
serological tests were performed for Borrelia burgdorferi, Babesia microti, and Ehrlichia equi; polymerase chain
reaction was performed to detect granulocytic Ehrlichia rDNA. Seventeen (27%) of 62 eligible patients had
laboratory evidence of tickborne infection, including 7 (11%) with probable Lyme disease only, 8 (13%) with
HGE only, and 2 (3%) with apparent coinfection. No patients with Babesia infection were identified. Patients
with and without tickborne infection were similar with regard to age, sex, symptoms, history of tick bite, and
outdoor exposure. The results suggest that tickborne infections are an important cause of nonspecific febrile
illness during the tick season in northwestern Wisconsin

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